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Identification of a novel conserved signaling motif in CD200 receptor required for its inhibitory function
The inhibitory signaling of CD200 receptor 1 (CD200R) has been attributed to its NPxY signaling motif. However, NPxY-motifs are present in multiple protein families and are mostly known to mediate protein trafficking between subcellular locations rather than signaling. Therefore, we investigated whe...
Autores principales: | Timmerman, Laura M., de Graaf, J. Fréderique, Satravelas, Nikolaos, Kesmir, Çan, Meyaard, Linde, van der Vlist, Michiel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007030/ https://www.ncbi.nlm.nih.gov/pubmed/33780466 http://dx.doi.org/10.1371/journal.pone.0244770 |
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