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Reduction of fibrosis and immune suppressive cells in ErbB2-dependent tumorigenesis by an LXR agonist

One of the central challenges for cancer therapy is the identification of factors in the tumor microenvironment that increase tumor progression and prevent immune surveillance. One such element associated with breast cancer is stromal fibrosis, a histopathologic criterion for invasive cancer and poo...

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Detalles Bibliográficos
Autores principales: Sheng, Gao, Yuan, Hongyan, Jin, Lu, Ranjit, Suman, Panov, Julia, Lu, Xun, Levi, Moshe, Glazer, Robert I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007044/
https://www.ncbi.nlm.nih.gov/pubmed/33780491
http://dx.doi.org/10.1371/journal.pone.0248996