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Elements and evolutionary determinants of genomic divergence between paired primary and metastatic tumors

Can metastatic-primary (M-P) genomic divergence measured from next generation sequencing reveal the natural history of metastatic dissemination? This remains an open question of utmost importance in facilitating a deeper understanding of metastatic progression, and thereby, improving its prevention....

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Detalles Bibliográficos
Autores principales: Sun, Ruping, Nikolakopoulos, Athanasios N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007046/
https://www.ncbi.nlm.nih.gov/pubmed/33730105
http://dx.doi.org/10.1371/journal.pcbi.1008838