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Therapeutic Potential of Phosphodiesterase Inhibitors against Neurodegeneration: The Perspective of the Medicinal Chemist

[Image: see text] Increasing human life expectancy prompts the development of novel remedies for cognitive decline: 44 million people worldwide are affected by dementia, and this number is predicted to triple by 2050. Acetylcholinesterase and N-methyl-d-aspartate receptors represent the targets of c...

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Detalles Bibliográficos
Autores principales: Ribaudo, Giovanni, Ongaro, Alberto, Zagotto, Giuseppe, Memo, Maurizio, Gianoncelli, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007108/
https://www.ncbi.nlm.nih.gov/pubmed/32401481
http://dx.doi.org/10.1021/acschemneuro.0c00244