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HIV-1 Nef counteracts autophagy restriction by enhancing the association between BECN1 and its inhibitor BCL2 in a PRKN-dependent manner

Macroautophagy/autophagy is an auto-digestive pro-survival pathway activated in response to stress to target cargo for lysosomal degradation. In recent years, autophagy has become prominent as an innate antiviral defense mechanism through multiple processes, such as targeting virions and viral compo...

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Detalles Bibliográficos
Autores principales: Castro-Gonzalez, Sergio, Shi, Yuhang, Colomer-Lluch, Marta, Song, Ying, Mowery, Kaitlyn, Almodovar, Sharilyn, Bansal, Anju, Kirchhoff, Frank, Sparrer, Konstantin, Liang, Chengyu, Serra-Moreno, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007141/
https://www.ncbi.nlm.nih.gov/pubmed/32097085
http://dx.doi.org/10.1080/15548627.2020.1725401