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HIV-1 Nef counteracts autophagy restriction by enhancing the association between BECN1 and its inhibitor BCL2 in a PRKN-dependent manner
Macroautophagy/autophagy is an auto-digestive pro-survival pathway activated in response to stress to target cargo for lysosomal degradation. In recent years, autophagy has become prominent as an innate antiviral defense mechanism through multiple processes, such as targeting virions and viral compo...
Autores principales: | Castro-Gonzalez, Sergio, Shi, Yuhang, Colomer-Lluch, Marta, Song, Ying, Mowery, Kaitlyn, Almodovar, Sharilyn, Bansal, Anju, Kirchhoff, Frank, Sparrer, Konstantin, Liang, Chengyu, Serra-Moreno, Ruth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007141/ https://www.ncbi.nlm.nih.gov/pubmed/32097085 http://dx.doi.org/10.1080/15548627.2020.1725401 |
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