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Bromodomain protein BRD4 is an epigenetic activator of B7-H6 expression in acute myeloid leukemia

B7-H6, a ligand for the NK activating receptor NKp30, has been identified as a biomarker of poor prognosis in several solid cancers. However, little is known about the role of B7-H6 and the mechanisms that control its expression in acute myeloid leukemia (AML). Epigenome modulation, including epigen...

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Detalles Bibliográficos
Autores principales: Baragaño Raneros, Aroa, Rodriguez, Ramon M, Bernardo Flórez, Aida, Palomo, Pilar, Colado, Enrique, Minguela, Alfredo, Suárez Álvarez, Beatriz, López-Larrea, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007156/
https://www.ncbi.nlm.nih.gov/pubmed/33796404
http://dx.doi.org/10.1080/2162402X.2021.1897294