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Bromodomain protein BRD4 is an epigenetic activator of B7-H6 expression in acute myeloid leukemia
B7-H6, a ligand for the NK activating receptor NKp30, has been identified as a biomarker of poor prognosis in several solid cancers. However, little is known about the role of B7-H6 and the mechanisms that control its expression in acute myeloid leukemia (AML). Epigenome modulation, including epigen...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007156/ https://www.ncbi.nlm.nih.gov/pubmed/33796404 http://dx.doi.org/10.1080/2162402X.2021.1897294 |