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Overexpression of mfpA Gene Increases Ciprofloxacin Resistance in Mycobacterium smegmatis
Fluoroquinolones (FQs) are antibiotics useful in the treatment of drug-resistant tuberculosis, but FQ-resistant mutants can be selected rapidly. Although mutations in the DNA gyrase are the principal cause of this resistance, pentapeptide proteins have been found to confer low-level FQ resistance in...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007378/ https://www.ncbi.nlm.nih.gov/pubmed/33824663 http://dx.doi.org/10.1155/2021/6689186 |