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Overexpression of mfpA Gene Increases Ciprofloxacin Resistance in Mycobacterium smegmatis

Fluoroquinolones (FQs) are antibiotics useful in the treatment of drug-resistant tuberculosis, but FQ-resistant mutants can be selected rapidly. Although mutations in the DNA gyrase are the principal cause of this resistance, pentapeptide proteins have been found to confer low-level FQ resistance in...

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Detalles Bibliográficos
Autores principales: Falco, Aura, Aranaga, Carlos, Ocampo, Ivan, Takiff, Howard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007378/
https://www.ncbi.nlm.nih.gov/pubmed/33824663
http://dx.doi.org/10.1155/2021/6689186