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Alleviation of Inflammation and Oxidative Stress in Pressure Overload-Induced Cardiac Remodeling and Heart Failure via IL-6/STAT3 Inhibition by Raloxifene

BACKGROUND: Inflammation and oxidative stress are involved in the initiation and progress of heart failure (HF). However, the role of the IL6/STAT3 pathway in the pressure overload-induced HF remains controversial. METHODS AND RESULTS: Transverse aortic constriction (TAC) was used to induce pressure...

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Detalles Bibliográficos
Autores principales: Huo, Shengqi, Shi, Wei, Ma, Haiyan, Yan, Dan, Luo, Pengcheng, Guo, Junyi, Li, Chenglong, Lin, Jiayuh, Zhang, Cuntai, Li, Sheng, Lv, Jiagao, Lin, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007383/
https://www.ncbi.nlm.nih.gov/pubmed/33824698
http://dx.doi.org/10.1155/2021/6699054