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Muscle Tissue as a Surrogate for In Vitro Drug Release Testing of Parenteral Depot Microspheres

Despite the importance of drug release testing of parenteral depot formulations, the current in vitro methods still require ameliorations in biorelevance. We have investigated here the use of muscle tissue components to better mimic the intramuscular administration. For convenient handling, muscle t...

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Detalles Bibliográficos
Autores principales: Kozak, Jan, Rabiskova, Miloslava, Lamprecht, Alf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007510/
https://www.ncbi.nlm.nih.gov/pubmed/33782794
http://dx.doi.org/10.1208/s12249-021-01965-4