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Muscle Tissue as a Surrogate for In Vitro Drug Release Testing of Parenteral Depot Microspheres
Despite the importance of drug release testing of parenteral depot formulations, the current in vitro methods still require ameliorations in biorelevance. We have investigated here the use of muscle tissue components to better mimic the intramuscular administration. For convenient handling, muscle t...
Autores principales: | Kozak, Jan, Rabiskova, Miloslava, Lamprecht, Alf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007510/ https://www.ncbi.nlm.nih.gov/pubmed/33782794 http://dx.doi.org/10.1208/s12249-021-01965-4 |
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