Biochemical and structural characterization of analogs of MRE11 breast cancer-associated mutant F237C

The MRE11–RAD50–NBS1 (MRN) protein complex plays a vital role in DNA double strand break sensing, signaling, and repair. Mutation in any component of this complex may lead to disease as disrupting DNA double strand break repair has the potential to cause translocations and loss of genomic informatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Rahman, Samiur, Beikzadeh, Mahtab, Latham, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007570/
https://www.ncbi.nlm.nih.gov/pubmed/33782469
http://dx.doi.org/10.1038/s41598-021-86552-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007570/
https://www.ncbi.nlm.nih.gov/pubmed/33782469
http://dx.doi.org/10.1038/s41598-021-86552-0

Ejemplares similares