mmsig: a fitting approach to accurately identify somatic mutational signatures in hematological malignancies

Mutational signatures have emerged as powerful biomarkers in cancer patients, with prognostic and therapeutic implications. Wider clinical utility requires access to reproducible algorithms, which allow characterization of mutational signatures in a given tumor sample. Here, we show how mutational s...

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Detalles Bibliográficos
Autores principales: Rustad, Even H., Nadeu, Ferran, Angelopoulos, Nicos, Ziccheddu, Bachisio, Bolli, Niccolò, Puente, Xose S., Campo, Elias, Landgren, Ola, Maura, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007623/
https://www.ncbi.nlm.nih.gov/pubmed/33782531
http://dx.doi.org/10.1038/s42003-021-01938-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007623/
https://www.ncbi.nlm.nih.gov/pubmed/33782531
http://dx.doi.org/10.1038/s42003-021-01938-0

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