Ibuprofen alters epoxide hydrolase activity and epoxy-oxylipin metabolites associated with different metabolic pathways in murine livers

Over the last decade oxylipins have become more recognized for their involvement in several diseases. Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen are known to inhibit cyclooxygenase (COX) enzymes, but how NSAIDs affect oxylipins, in addition to COX products, in animal tissues is...

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Detalles Bibliográficos
Autores principales: Tiwari, Shuchita, Yang, Jun, Morisseau, Christophe, Durbin-Johnson, Blythe, Hammock, Bruce D., Gomes, Aldrin V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007717/
https://www.ncbi.nlm.nih.gov/pubmed/33782432
http://dx.doi.org/10.1038/s41598-021-86284-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007717/
https://www.ncbi.nlm.nih.gov/pubmed/33782432
http://dx.doi.org/10.1038/s41598-021-86284-1

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