Cargando…
Developing a medium combination to attain similar glycosylation profile to originator by DoE and cluster analysis method
Glycosylation is critical for monoclonal antibody production because of its impact on pharmacokinetics and pharmacodynamics. Modulation of glycan profile is frequently needed in biosimilar development. However, glycosylation profile is not a single value like that of cell culture titer, hence making...
Autores principales: | Xu, Jian, Shao, Zhihui, Wang, Zhanqing, Huang, Yingfeng, Zou, Xun, Shen, Yaling |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007809/ https://www.ncbi.nlm.nih.gov/pubmed/33782463 http://dx.doi.org/10.1038/s41598-021-86447-0 |
Ejemplares similares
-
Similarities and Differences in the Glycosylation Mechanisms in Prokaryotes and Eukaryotes
por: Dell, Anne, et al.
Publicado: (2010) -
Attaining superhigh energies with e+e- collisions
por: Amaldi, Ugo
Publicado: (1989) -
Does Educational Attainment Affect Residents’ Health?
por: Long, Cuihong, et al.
Publicado: (2020) -
Educational attainment does not influence brain aging
por: Nyberg, Lars, et al.
Publicado: (2021) -
Using Cluster Analysis to Explore Engagement and e-Attainment as Emergent Behavior in Electronic Mental Health
por: Sanatkar, Samineh, et al.
Publicado: (2019)