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Early escitalopram administration as a preemptive treatment strategy against spasticity after contusive spinal cord injury in rats

In the majority of spinal cord injury (SCI) patients, spasticity develops in the subacute phase and chronically persists with muscle hypertonia. Among various pathological conditions underlying spasticity, upregulated expression of 5-HT receptors (5-HTR) on the spinal motor neurons due to 5-HT dener...

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Detalles Bibliográficos
Autores principales: Ryu, Youngjae, Ogata, Toru, Nagao, Motoshi, Sawada, Yasuhiro, Nishimura, Ryohei, Fujita, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007832/
https://www.ncbi.nlm.nih.gov/pubmed/33782426
http://dx.doi.org/10.1038/s41598-021-85961-5