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Early escitalopram administration as a preemptive treatment strategy against spasticity after contusive spinal cord injury in rats
In the majority of spinal cord injury (SCI) patients, spasticity develops in the subacute phase and chronically persists with muscle hypertonia. Among various pathological conditions underlying spasticity, upregulated expression of 5-HT receptors (5-HTR) on the spinal motor neurons due to 5-HT dener...
Autores principales: | Ryu, Youngjae, Ogata, Toru, Nagao, Motoshi, Sawada, Yasuhiro, Nishimura, Ryohei, Fujita, Naoki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007832/ https://www.ncbi.nlm.nih.gov/pubmed/33782426 http://dx.doi.org/10.1038/s41598-021-85961-5 |
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