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Frequency of Gluten-Reactive T Cells in Active Celiac Lesions Estimated by Direct Cell Cloning

Chronic inflammation of the small intestine in celiac disease is driven by activation of CD4+ T cells that recognize gluten peptides presented by disease-associated HLA-DQ molecules. We have performed direct cell cloning of duodenal biopsies from five untreated and one refractory celiac disease pati...

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Detalles Bibliográficos
Autores principales: Qiao, Shuo-Wang, Dahal-Koirala, Shiva, Eggesbø, Linn M., Lundin, Knut E. A., Sollid, Ludvig M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007869/
https://www.ncbi.nlm.nih.gov/pubmed/33796112
http://dx.doi.org/10.3389/fimmu.2021.646163