Chitotriosidase Activity Is Counterproductive in a Mouse Model of Systemic Candidiasis

Mammalian cells do not produce chitin, an insoluble polymer of N-acetyl-D-glucosamine (GlcNAc), although chitin is a structural component of the cell wall of pathogenic microorganisms such as Candida albicans. Mammalian cells, including cells of the innate immune system elaborate chitinases, includi...

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Detalles Bibliográficos
Autores principales: Schmitz, Nicholas A., Thakare, Ritesh P., Chung, Chun-Shiang, Lee, Chang-Min, Elias, Jack A., Lee, Chun Geun, LeBlanc, Brian W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007879/
https://www.ncbi.nlm.nih.gov/pubmed/33796101
http://dx.doi.org/10.3389/fimmu.2021.626798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007879/
https://www.ncbi.nlm.nih.gov/pubmed/33796101
http://dx.doi.org/10.3389/fimmu.2021.626798

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