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Chitotriosidase Activity Is Counterproductive in a Mouse Model of Systemic Candidiasis
Mammalian cells do not produce chitin, an insoluble polymer of N-acetyl-D-glucosamine (GlcNAc), although chitin is a structural component of the cell wall of pathogenic microorganisms such as Candida albicans. Mammalian cells, including cells of the innate immune system elaborate chitinases, includi...
Autores principales: | Schmitz, Nicholas A., Thakare, Ritesh P., Chung, Chun-Shiang, Lee, Chang-Min, Elias, Jack A., Lee, Chun Geun, LeBlanc, Brian W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007879/ https://www.ncbi.nlm.nih.gov/pubmed/33796101 http://dx.doi.org/10.3389/fimmu.2021.626798 |
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