High Expression of Interleukin-3 Receptor Alpha Chain (CD123) Predicts Favorable Outcome in Pediatric B-Cell Acute Lymphoblastic Leukemia Lacking Prognosis-Defining Genomic Aberrations

BACKGROUND: Aberrant expression of CD123 (IL-3Rα) was observed in various hematological malignancies including acute lymphoblastic leukemia (ALL), which is the most common malignancy in childhood. Although widely used for minimal residual disease (MRD) monitoring, the prognostic value of CD123 has n...

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Detalles Bibliográficos
Autores principales: Li, Zhiheng, Chu, Xinran, Gao, Li, Ling, Jing, Xiao, Peifang, Lu, Jun, Wang, Yi, He, Hailong, Li, Jianqin, Hu, Yixin, Li, Jie, Pan, Jian, Xiao, Sheng, Hu, Shaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008053/
https://www.ncbi.nlm.nih.gov/pubmed/33796456
http://dx.doi.org/10.3389/fonc.2021.614420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008053/
https://www.ncbi.nlm.nih.gov/pubmed/33796456
http://dx.doi.org/10.3389/fonc.2021.614420

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