Enteropeptidase inhibitor SCO-792 effectively prevents kidney function decline and fibrosis in a rat model of chronic kidney disease

BACKGROUND: Inhibiting enteropeptidase, a gut serine protease regulating protein digestion, suppresses food intake and ameliorates obesity and diabetes in mice. However, the effects of enteropeptidase inhibition on kidney parameters are largely unknown. Here, we evaluated the chronic effects of an e...

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Detalles Bibliográficos
Autores principales: Katayama, Yuko, Sugama, Jun, Suzuki, Tomohisa, Ishimura, Yoshimasa, Kobayashi, Akihiro, Moritoh, Yusuke, Watanabe, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008362/
https://www.ncbi.nlm.nih.gov/pubmed/33351150
http://dx.doi.org/10.1093/ndt/gfaa349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008362/
https://www.ncbi.nlm.nih.gov/pubmed/33351150
http://dx.doi.org/10.1093/ndt/gfaa349

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