In Vivo Functional Effects of CYP2C9 M1L, a Novel and Common Variant in the Yup’ik Alaska Native Population

Alaska Native people are under-represented in genetic research but have unique gene variation that may critically impact their response to pharmacotherapy. Full resequencing of CYP2C9 in a cross-section of this population identified CYP2C9 Met1Leu (M1L), a novel, relatively common single nucleotide...

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Detalles Bibliográficos
Autores principales: Henderson, Lindsay M., Hopkins, Scarlett E., Boyer, Bert B., Thornton, Timothy A., Rettie, Allan E., Thummel, Kenneth E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008381/
https://www.ncbi.nlm.nih.gov/pubmed/33632714
http://dx.doi.org/10.1124/dmd.120.000301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008381/
https://www.ncbi.nlm.nih.gov/pubmed/33632714
http://dx.doi.org/10.1124/dmd.120.000301

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