Efficient and flexible simulation-based sample size determination for clinical trials with multiple design parameters

Simulation offers a simple and flexible way to estimate the power of a clinical trial when analytic formulae are not available. The computational burden of using simulation has, however, restricted its application to only the simplest of sample size determination problems, often minimising a single...

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Detalles Bibliográficos
Autores principales: Wilson, Duncan T, Hooper, Richard, Brown, Julia, Farrin, Amanda J, Walwyn, Rebecca EA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008419/
https://www.ncbi.nlm.nih.gov/pubmed/33267735
http://dx.doi.org/10.1177/0962280220975790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008419/
https://www.ncbi.nlm.nih.gov/pubmed/33267735
http://dx.doi.org/10.1177/0962280220975790

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