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Human ancient DNA analyses reveal the high burden of tuberculosis in Europeans over the last 2,000 years

Tuberculosis (TB), usually caused by Mycobacterium tuberculosis bacteria, is the first cause of death from an infectious disease at the worldwide scale, yet the mode and tempo of TB pressure on humans remain unknown. The recent discovery that homozygotes for the P1104A polymorphism of TYK2 are at hi...

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Detalles Bibliográficos
Autores principales: Kerner, Gaspard, Laval, Guillaume, Patin, Etienne, Boisson-Dupuis, Stéphanie, Abel, Laurent, Casanova, Jean-Laurent, Quintana-Murci, Lluis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008489/
https://www.ncbi.nlm.nih.gov/pubmed/33667394
http://dx.doi.org/10.1016/j.ajhg.2021.02.009