Cargando…

PPARγ activation improves the microenvironment of perivascular adipose tissue and attenuates aortic stiffening in obesity

BACKGROUND: Obesity-related cardiovascular risk, end points, and mortality are strongly related to arterial stiffening. Current therapeutic approaches for arterial stiffening are not focused on direct targeting within the vessel. Perivascular adipose tissue (PVAT) surrounding the artery has been sho...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Ju-Yi, Wu, Yi-Pin, Li, Chih-Yi, Jheng, Huei-Fen, Kao, Ling-Zhen, Yang, Ching-Chun, Leu, Sy-Ying, Lien, I-Chia, Weng, Wen-Tsan, Tai, Haw-Chih, Chiou, Yu-Wei, Tang, Ming-Jer, Tsai, Pei-Jane, Tsai, Yau-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008548/
https://www.ncbi.nlm.nih.gov/pubmed/33781257
http://dx.doi.org/10.1186/s12929-021-00720-y