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PPARγ activation improves the microenvironment of perivascular adipose tissue and attenuates aortic stiffening in obesity
BACKGROUND: Obesity-related cardiovascular risk, end points, and mortality are strongly related to arterial stiffening. Current therapeutic approaches for arterial stiffening are not focused on direct targeting within the vessel. Perivascular adipose tissue (PVAT) surrounding the artery has been sho...
Autores principales: | Chen, Ju-Yi, Wu, Yi-Pin, Li, Chih-Yi, Jheng, Huei-Fen, Kao, Ling-Zhen, Yang, Ching-Chun, Leu, Sy-Ying, Lien, I-Chia, Weng, Wen-Tsan, Tai, Haw-Chih, Chiou, Yu-Wei, Tang, Ming-Jer, Tsai, Pei-Jane, Tsai, Yau-Sheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008548/ https://www.ncbi.nlm.nih.gov/pubmed/33781257 http://dx.doi.org/10.1186/s12929-021-00720-y |
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