miR-133a silencing rescues glucocorticoid-induced bone loss by regulating the MAPK/ERK signaling pathway

BACKGROUND: Dysfunction of mesenchymal stem cells (MSCs) is recognized as critical to the pathogenesis of glucocorticoid-induced osteoporosis (GIO), suggesting the potential of MSC-targeting interventions for this disorder. As the miR-133a has been shown to play an important role in bone metabolism,...

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Detalles Bibliográficos
Autores principales: Wang, Gang, Wang, Fengbin, Zhang, Lecheng, Yan, Chao, Zhang, Yuelei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008567/
https://www.ncbi.nlm.nih.gov/pubmed/33781345
http://dx.doi.org/10.1186/s13287-021-02278-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008567/
https://www.ncbi.nlm.nih.gov/pubmed/33781345
http://dx.doi.org/10.1186/s13287-021-02278-w

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