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miR-133a silencing rescues glucocorticoid-induced bone loss by regulating the MAPK/ERK signaling pathway

BACKGROUND: Dysfunction of mesenchymal stem cells (MSCs) is recognized as critical to the pathogenesis of glucocorticoid-induced osteoporosis (GIO), suggesting the potential of MSC-targeting interventions for this disorder. As the miR-133a has been shown to play an important role in bone metabolism,...

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Detalles Bibliográficos
Autores principales:	Wang, Gang, Wang, Fengbin, Zhang, Lecheng, Yan, Chao, Zhang, Yuelei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008567/ https://www.ncbi.nlm.nih.gov/pubmed/33781345 http://dx.doi.org/10.1186/s13287-021-02278-w

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