Human DNA decays faster with time than viral dsDNA: an analysis on HPV16 using pathology archive samples spanning 85 years

BACKGROUND: Quality of the nucleic acids extracted from Formalin Fixed Paraffin Embedded (FFPE) samples largely depends on pre-analytic, fixation and storage conditions. We assessed the differential sensitivity of viral and human double stranded DNA (dsDNA) to degradation with storage time. METHODS:...

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Detalles Bibliográficos
Autores principales: Nicolás-Párraga, Sara, Torres, Montserrat, Alemany, Laia, Félix, Ana, Cruz, Eugenia, de Sanjosé, Silvia, Bosch, Francesc Xavier, Bravo, Ignacio G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008572/
https://www.ncbi.nlm.nih.gov/pubmed/33781303
http://dx.doi.org/10.1186/s12985-021-01529-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008572/
https://www.ncbi.nlm.nih.gov/pubmed/33781303
http://dx.doi.org/10.1186/s12985-021-01529-9

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