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Plasma pTau181 predicts cortical brain atrophy in aging and Alzheimer’s disease

BACKGROUND: To investigate the association of plasma pTau181, assessed with a new immunoassay, with neurodegeneration of white matter and gray matter cross-sectionally and longitudinally, in aging and Alzheimer’s disease. METHODS: Observational data was obtained from the Alzheimer’s Disease Neuroima...

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Detalles Bibliográficos
Autores principales: Tissot, Cécile, L. Benedet, Andréa, Therriault, Joseph, Pascoal, Tharick A., Lussier, Firoza Z., Saha-Chaudhuri, Paramita, Chamoun, Mira, Savard, Melissa, Mathotaarachchi, Sulantha S., Bezgin, Gleb, Wang, Yi-Ting, Fernandez Arias, Jaime, Rodriguez, Juan Lantero, Snellman, Anniina, Ashton, Nicholas J., Karikari, Thomas K., Blennow, Kaj, Zetterberg, Henrik, De Villers-Sidani, Etienne, Huot, Philippe, Gauthier, Serge, Rosa-Neto, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008680/
https://www.ncbi.nlm.nih.gov/pubmed/33781319
http://dx.doi.org/10.1186/s13195-021-00802-x