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Viscoelastic properties of white and gray matter-derived microglia differentiate upon treatment with lipopolysaccharide but not upon treatment with myelin

BACKGROUND: The biomechanical properties of the brain have increasingly been shown to relate to brain pathology in neurological diseases, including multiple sclerosis (MS). Inflammation and demyelination in MS induce significant changes in brain stiffness which can be linked to the relative abundanc...

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Detalles Bibliográficos
Autores principales: van Wageningen, Thecla A., Antonovaite, Nelda, Paardekam, Erik, Brevé, John J. P., Iannuzzi, Davide, van Dam, Anne-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008683/
https://www.ncbi.nlm.nih.gov/pubmed/33781276
http://dx.doi.org/10.1186/s12974-021-02134-x