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Machine learning predicts nucleosome binding modes of transcription factors

BACKGROUND: Most transcription factors (TFs) compete with nucleosomes to gain access to their cognate binding sites. Recent studies have identified several TF-nucleosome interaction modes including end binding (EB), oriented binding, periodic binding, dyad binding, groove binding, and gyre spanning....

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Detalles Bibliográficos
Autores principales: Kishan, K. C., Subramanya, Sridevi K., Li, Rui, Cui, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008688/
https://www.ncbi.nlm.nih.gov/pubmed/33784978
http://dx.doi.org/10.1186/s12859-021-04093-9