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Aldosterone-Regulating Receptors and Aldosterone-Driver Somatic Mutations

BACKGROUND: Somatic gene mutations that facilitate inappropriate intracellular calcium entrance have been identified in most aldosterone-producing adenomas (APAs). Studies suggest that angiotensin II and adrenocorticotropic hormone (ACTH) augment aldosterone production from APAs. Little is known, ho...

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Detalles Bibliográficos
Autores principales: Lim, Jung Soo, Plaska, Samuel W., Rege, Juilee, Rainey, William E., Turcu, Adina F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008747/
https://www.ncbi.nlm.nih.gov/pubmed/33796077
http://dx.doi.org/10.3389/fendo.2021.644382