The Wnt signaling receptor Fzd9 is essential for Myc-driven tumorigenesis in pancreatic islets

The huge cadre of genes regulated by Myc has obstructed the identification of critical effectors that are essential for Myc-driven tumorigenesis. Here, we describe how only the lack of the receptor Fzd9, previously identified as a Myc transcriptional target, impairs sustained tumor expansion and β-c...

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Detalles Bibliográficos
Autores principales: Zacarías-Fluck, Mariano F, Jauset, Toni, Martínez-Martín, Sandra, Kaur, Jastrinjan, Casacuberta-Serra, Sílvia, Massó-Vallés, Daniel, Serrano del Pozo, Erika, Martín-Fernández, Génesis, González-Larreategui, Íñigo, López-Estévez, Sergio, Brown-Swigart, Lamorna, Beaulieu, Marie-Eve, Whitfield, Jonathan R, Madan, Babita, Virshup, David M, Evan, Gerard I, Soucek, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008953/
https://www.ncbi.nlm.nih.gov/pubmed/33653688
http://dx.doi.org/10.26508/lsa.201900490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008953/
https://www.ncbi.nlm.nih.gov/pubmed/33653688
http://dx.doi.org/10.26508/lsa.201900490

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