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The Functions and Mechanisms of PR-DUB in Malignancy

The interplay between cancer genome and deregulated epigenomic control is critical for cancer initiation and progression. ASXL1 (Additional Sex combs-like 1) is frequently mutated in tumors especially myeloid malignancies. However, there remains a debate whether the mutations are loss or gain-of-fun...

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Detalles Bibliográficos
Autores principales: Cao, Lei, Li, Rui, Wu, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008992/
https://www.ncbi.nlm.nih.gov/pubmed/33796551
http://dx.doi.org/10.3389/fmolb.2021.657150