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Pharmacoinformatics-based identification of transmembrane protease serine-2 inhibitors from Morus Alba as SARS-CoV-2 cell entry inhibitors

ABSTRACT: Transmembrane protease serine-2 (TMPRSS2) is a cell-surface protein expressed by epithelial cells of specific tissues including those in the aerodigestive tract. It helps the entry of novel coronavirus (n-CoV) or Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in the host cell...

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Detalles Bibliográficos
Autores principales: Shakya, Anshul, Chikhale, Rupesh V., Bhat, Hans Raj, Alasmary, Fatmah Ali, Almutairi, Tahani Mazyad, Ghosh, Surajit Kumar, Alhajri, Hassna Mohammed, Alissa, Siham A., Nagar, Shuchi, Islam, Md Ataul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009078/
https://www.ncbi.nlm.nih.gov/pubmed/33786727
http://dx.doi.org/10.1007/s11030-021-10209-3