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In vivo therapeutic success of MicroRNA-155 antagomir in a mouse model of pulmonary fibrosis induced by bleomycin

BACKGROUND/AIMS: MicroRNAs (miRNAs) play critical regulatory roles in the pathogenesis of pulmonary fibrosis. The aim of this study was to explore whether miRNA antagomirs could serve as potential therapeutic agents in interstitial lung diseases. METHODS: A mouse model of pulmonary fibrosis was esta...

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Detalles Bibliográficos
Autores principales: Sun, Xiaoyuan, Kang, Yu, Xue, Shan, Zou, Jing, Xu, Jiabo, Tang, Daoqiang, Qin, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Internal Medicine 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009162/
https://www.ncbi.nlm.nih.gov/pubmed/32506869
http://dx.doi.org/10.3904/kjim.2019.098