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CARD-Associated Risk Score Features the Immune Landscape and Predicts the Responsiveness to Anti-PD-1 Therapy in IDH Wild-Type Gliomas

BACKGROUND: Proteins containing the caspase recruitment domain (CARD) play critical roles in cell apoptosis and immunity. However, the impact of CARD genes in tumor immune cell infiltration, responsiveness to checkpoint immunotherapy, and clinical outcomes of gliomas remains unclear. Here, we explor...

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Detalles Bibliográficos
Autores principales: Li, Depei, Hu, Wanming, Lin, Xiaoping, Zhang, Ji, He, Zhenqiang, Zhong, Sheng, Wen, Xia, Zhang, Peiyu, Jiang, Xiaobing, Duan, Hao, Guo, Chengcheng, Wang, Jian, Zeng, Jing, Chen, Zhongping, Mou, Yonggao, Sai, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009185/
https://www.ncbi.nlm.nih.gov/pubmed/33796538
http://dx.doi.org/10.3389/fcell.2021.653240