Boosting GWAS using biological networks: A study on susceptibility to familial breast cancer

Genome-wide association studies (GWAS) explore the genetic causes of complex diseases. However, classical approaches ignore the biological context of the genetic variants and genes under study. To address this shortcoming, one can use biological networks, which model functional relationships, to sea...

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Detalles Bibliográficos
Autores principales: Climente-González, Héctor, Lonjou, Christine, Lesueur, Fabienne, Stoppa-Lyonnet, Dominique, Andrieu, Nadine, Azencott, Chloé-Agathe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009366/
https://www.ncbi.nlm.nih.gov/pubmed/33735170
http://dx.doi.org/10.1371/journal.pcbi.1008819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009366/
https://www.ncbi.nlm.nih.gov/pubmed/33735170
http://dx.doi.org/10.1371/journal.pcbi.1008819

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