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Boosting GWAS using biological networks: A study on susceptibility to familial breast cancer
Genome-wide association studies (GWAS) explore the genetic causes of complex diseases. However, classical approaches ignore the biological context of the genetic variants and genes under study. To address this shortcoming, one can use biological networks, which model functional relationships, to sea...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009366/ https://www.ncbi.nlm.nih.gov/pubmed/33735170 http://dx.doi.org/10.1371/journal.pcbi.1008819 |