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Behavior of dicentric chromosomes in budding yeast

DNA double-strand breaks arise in vivo when a dicentric chromosome (two centromeres on one chromosome) goes through mitosis with the two centromeres attached to opposite spindle pole bodies. Repair of the DSBs generates phenotypic diversity due to the range of monocentric derivative chromosomes that...

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Detalles Bibliográficos
Autores principales: Cook, Diana, Long, Sarah, Stanton, John, Cusick, Patrick, Lawrimore, Colleen, Yeh, Elaine, Grant, Sarah, Bloom, Kerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009378/
https://www.ncbi.nlm.nih.gov/pubmed/33735169
http://dx.doi.org/10.1371/journal.pgen.1009442