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Circular RNA circDtx1 regulates IRF3-mediated antiviral immune responses through suppression of miR-15a-5p-dependent TRIF downregulation in teleost fish

Circular RNAs (circRNAs) represent a class of widespread and diverse covalently closed circular endogenous RNAs that exert crucial functions in regulating gene expression in mammals. However, the function and regulation mechanism of circRNAs in lower vertebrates are still unknown. Here, we discovere...

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Detalles Bibliográficos
Autores principales: Zheng, Weiwei, Chu, Qing, Yang, Liyuan, Sun, Lingping, Xu, Tianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009406/
https://www.ncbi.nlm.nih.gov/pubmed/33735323
http://dx.doi.org/10.1371/journal.ppat.1009438