Characterization of a broadly specific cadaverine N-hydroxylase involved in desferrioxamine B biosynthesis in Streptomyces sviceus

N-hydroxylating flavin-dependent monooxygenases (FMOs) are involved in the biosynthesis of hydroxamate siderophores, playing a key role in microbial virulence. Herein, we report the first structural and kinetic characterization of a novel alkyl diamine N-hydroxylase DesB from Streptomyces sviceus (S...

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Detalles Bibliográficos
Autores principales: Giddings, Lesley-Ann, Lountos, George T., Kim, Kang Woo, Brockley, Matthew, Needle, Danielle, Cherry, Scott, Tropea, Joseph E., Waugh, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009421/
https://www.ncbi.nlm.nih.gov/pubmed/33784308
http://dx.doi.org/10.1371/journal.pone.0248385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009421/
https://www.ncbi.nlm.nih.gov/pubmed/33784308
http://dx.doi.org/10.1371/journal.pone.0248385

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