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Characterization of a broadly specific cadaverine N-hydroxylase involved in desferrioxamine B biosynthesis in Streptomyces sviceus
N-hydroxylating flavin-dependent monooxygenases (FMOs) are involved in the biosynthesis of hydroxamate siderophores, playing a key role in microbial virulence. Herein, we report the first structural and kinetic characterization of a novel alkyl diamine N-hydroxylase DesB from Streptomyces sviceus (S...
Autores principales: | Giddings, Lesley-Ann, Lountos, George T., Kim, Kang Woo, Brockley, Matthew, Needle, Danielle, Cherry, Scott, Tropea, Joseph E., Waugh, David S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009421/ https://www.ncbi.nlm.nih.gov/pubmed/33784308 http://dx.doi.org/10.1371/journal.pone.0248385 |
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