Light chain skewing in autoantibodies and B-cell receptors of the citrullinated antigen-binding B-cell response in rheumatoid arthritis

Rheumatoid arthritis (RA) is a chronic autoimmune disease affecting 1% of the world population. RA is associated with the presence of autoantibodies, of which anti-citrullinated protein antibodies (ACPA) are most prominent. ACPA are produced by citrullinated antigen-binding B cells that have presuma...

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Detalles Bibliográficos
Autores principales: Slot, Linda M., Vergroesen, Rochelle D., Kerkman, Priscilla F., Staudinger, Ellen, Reijm, Sanne, van Dooren, Hugo J., van der Voort, Ellen I. H., Huizinga, Tom W. J., Toes, René E. M., Scherer, Hans U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009422/
https://www.ncbi.nlm.nih.gov/pubmed/33784344
http://dx.doi.org/10.1371/journal.pone.0247847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009422/
https://www.ncbi.nlm.nih.gov/pubmed/33784344
http://dx.doi.org/10.1371/journal.pone.0247847

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