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High initial IgG antibody levels against Orientia tsutsugamushi are associated with an increased risk of severe scrub typhus infection

BACKGROUND: Scrub typhus is a dominant cause of febrile illness in many parts of Asia. Immunity is limited by the great strain diversity of Orientia tsutsugamushi. It is unclear whether previous infection protects from severe infection or enhances the risk. METHODS/PRINCIPAL FINDINGS: We studied IgG...

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Detalles Bibliográficos
Autores principales: Devamani, Carol S., Prakash, John A. J., Alexander, Neal, Stone, William, Gunasekaran, Karthik, Rose, Winsley, Schmidt, Wolf-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009433/
https://www.ncbi.nlm.nih.gov/pubmed/33735183
http://dx.doi.org/10.1371/journal.pntd.0009283