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Anti-TWEAK Antibody Alleviates Renal Interstitial Fibrosis by Increasing PGC-1α Expression in Lupus Nephritis

PURPOSE: Current studies on the mechanism of tumor necrosis factor-like weak inducer of apoptosis (TWEAK) in lupus nephritis (LN) mainly focus on the inflammatory pathway. Herein, we aimed to determine whether TWEAK could promote the progression of renal interstitial fibrosis by regulating peroxisom...

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Detalles Bibliográficos
Autores principales: Xue, Leixi, Zhang, Yi, Xu, Jiajun, Lu, Wentian, Wang, Qing, Fu, Jinxiang, Liu, Zhichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009537/
https://www.ncbi.nlm.nih.gov/pubmed/33814923
http://dx.doi.org/10.2147/JIR.S301356