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Optic nerve regeneration screen identifies multiple genes restricting adult neural repair

Adult mammalian central nervous system (CNS) trauma interrupts neural networks and, because axonal regeneration is minimal, neurological deficits persist. Repair via axonal growth is limited by extracellular inhibitors and cell-autonomous factors. Based on results from a screen in vitro, we evaluate...

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Detalles Bibliográficos
Autores principales: Lindborg, Jane A., Tran, Nicholas M., Chenette, Devon M., DeLuca, Kristin, Foli, Yram, Kannan, Ramakrishnan, Sekine, Yuichi, Wang, Xingxing, Wollan, Marius, Kim, In-Jung, Sanes, Joshua R., Strittmatter, Stephen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009559/
https://www.ncbi.nlm.nih.gov/pubmed/33657370
http://dx.doi.org/10.1016/j.celrep.2021.108777