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Non-natural 3-Arylmorpholino-β-amino Acid as a PPII Helix Inducer
[Image: see text] A new non-natural β-amino acid, named 3-Ar-β-Morph, was designed and synthesized via a regio- and diastereoselective Pd-catalyzed C(sp(3))H-arylation of the corresponding 2S,6S-(6-methoxymorpholin-2-yl)carboxylic acid, readily available from glucose. According to the computational...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009597/ https://www.ncbi.nlm.nih.gov/pubmed/32790435 http://dx.doi.org/10.1021/acs.orglett.0c02331 |